Men with NOA azoospermia often have a genetic abnormality that has caused the lack of sperm, whereas most men with congenital absence of the vas deferens have abnormalities of the cystic fibrosis (CFTR) gene. Sperm quality in obstructive and non-obstructive azoospermia. The relationship of FSH with spermatogenesis is not straightforward in men with NOA. This is manifest by the range of FSH levels seen in the present study; in particular, successful sperm retrieval was seen in three men with FSH >90 IU/mL. This may reflect the effectiveness of micro-TESE in finding small areas of sperm production.Cited by: 118.
Nov 01, 2017 · Sperm retrievals in men with nonobstructive azoospermia (NOA) are challenging infertility cases. One strategy for finding sperm is microdissection TESE (mTESE), and another is fine needle aspiration (FNA) “mapping,” a diagnostic procedure that locates sperm through extensive needle sampling. We analyzed FNA maps performed after failed mTESE to evaluate if and where sperm Author: S. Jarvis, H.K. Yee, N.M. Thomas, K.C. Prasad, I. Cha, P.J. Turek. Azoospermia is the medical term used when there are no sperm in the ejaculate. It can be “obstructive,” where there is a blockage preventing sperm from entering the ejaculate, or it can be “nonobstructive” when it is due to decreased sperm production by the testis.
Variations of TESE that have been developed to improve the success rate of sperm retrieval for use in ICSI in men with NOA include microdissection TESE (microTESE), in which an operating microscope is used to identify and remove fuller seminiferous tubules within the testicle that are more likely to harbor spermatogenesis (Fig. 23.9). 81 MicroTESE, which results in the removal of much less testicular . Sep 01, 2002 · It should be mentioned that in NOA, testicular sperm may be retrieved also by performing testicular sperm aspiration (TESA); however, as sperm is produced focally, the chance of finding sperm is related to the amount of testicular tissue extracted.Cited by: 61.
Dec 15, 2015 · Nonobstructive azoospermia (NOA) is the most severe condition in male infertility and affects 10% of the infertile men.4 Before the availability of assisted reproductive technology (ART), only donor sperm provided a real chance of conception in couples affected by this condition. Dec 17, 2012 · Previous biopsy. Testicular biopsy can document normal sperm production, and therefore imply the presence of obstruction in normal testicular size with at least one palpable vas deferens and a normal serum FSH (diagnostic biopsy is also the treatment for men with NOA.Cited by: 108.