Sep 01, 2019 · A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Negative rheumatoid factor polyarthritis. The ANA, RF, and CCP tests are commonly used in adults in the workup of SLE and inflammatory arthritis. In general, physicians have assumed a similar diagnostic utility in diagnosing childhood rheumatic conditions. polyarthritis (RF Negative), polyarthritis (RF Positive), psoriatic Arthritis, enthesitis related arthritis.
Younger onset RF-negative polyarthritis patients are more likely to be antinuclear antibody (ANA) positive and are at greater risk for iridocyclitis. 17 A young onset age of RF-negative polyarthritis is associated with a less favorable long-term outcome. 18-20 Greenwald et al. 16 found 2-year outcomes in an older onset, RF-negative JIA subgroup. Uveitis can occur in other JIA subtypes such as rheumatoid factor (RF)-negative polyarthritis or psoriatic arthritis, especially if ANA-positive. As discussed later, there is evidence suggesting that ANA-positive patients represent a single disease entity, currently classified into different categories.